Liver Fungtion

liver is the center of metabolism throughout the body, is the source of the body's energy use by 20% and 20-25% of blood oxygen. There are several liver functions, namely:
Carbohydrate metabolism of liver function
Formation, and changes of KH solution, fats and proteins related to each other a similar .liver change the pentoses and hexoses are absorbed from the intestine into glycogen, this mechanism is called glikogenesis. And glycogen in the liver and then dumped in the liver glycogen to glucose would solve. Solving process of glucose called glycogen mjd glikogenelisis. because these processes, the liver is the main source of glucose in the body convert glucose through subsequent liver shunt monophosphat hexoses and pentoses formed. Pentose formation has several purposes: To generate energy, biosynthesis of nucleotides, nucleic acid and ATP, and forming / 3-carbon compound biosynthesis (3C) is piruvic acid (pyruvic acid required in the Krebs cycle).
Liver function as lipid metabolism
liver not only shape / synthesize fat but once entered katabolisis fatty acids fatty acids broken down into several components:
1. 4 carbon - Ketone Bodies
2. two carbon - ACTIVE acetate (broken down into fatty acids and glycerol)
3.binding cholesterol
4.binding and phospholipid solution
Liver is the main formation, synthesis, esterification and excretion of cholesterol. Where is the standard examination of serum cholesterol to lipid metabolism
Liver function as protein metabolism
Liver to synthesize many kinds of proteins from amino acids. deamination process, the liver also synthesizes glucose from fatty acids and acid transamination amino.Dengan process, the liver produces amino acids from non-nitrogenous substances. Liver is the only organ who form the plasma albumin and ∂ - globulin and the main organ for the production urea.Urea an end product of protein metabolism. ∂ - globulin in addition formed in the liver, was also formed in the spleen and bone marrow β - globulin was only formed in in hati.albumin containing 584 ± 66 000 amino acids with molecular
Liver function in relation to blood clotting
Liver is an important organ for the synthesis of proteins related to blood coagulation, for example: forming fibrinogen, protrombin, factor V, VII, IX, X. Taxable foreign body piercing the blood vessels - which is a factor ekstrinsi action, if any relationship with heart valve - the action is intrinsik.Fibrin factors have a strong let isomers pembekuannya and supplemented with the factor XIII, while the Vit K is required for the formation protrombin and several coagulation factors.
The function of the liver as vitamin metabolism
All the vitamins are stored in the liver, especially vitamins A, D, E, K
Liver function as detoksikation
The liver is the center of the body detoksikasi, detoksikasi process occurs in the process of oxidation, reduction, methylation, esterification and conjugation to a variety of materials such as toxic substances, drug overdose.
Liver function as phagocytosis and immunity
Tues Kupfer is an essential filter bacteria, pigments and other materials through the process of phagocytosis. Besides that Kupfer cells also co-produced ∂ - immune globulin as a mechanism livers.
Hemodynamic function
liver received a level ± 25% of cardiac output, blood flow to normal liver ± 1500 cc / min or 1000 to 1800 cc / min. Blood flowing in a.hepatica ± 25% and in 75% of all v.porta blood flow to the heart. Blood flow to the liver is influenced by mechanical factors, the influence of neural and hormonal, flow is changed rapidly at the time of exercise, sun, shock.Hepar an important organ for maintaining blood flow.